• Top 200 Drugs Podcast – Drugs 31-35
    Jul 18 2024
    On this episode of the Real Life Pharmacology podcast, I discuss drugs 31-35 of the top 200 drugs. Ethinyl estradiol/drospirenone is a combined oral contraceptive used for birth control purposes. Hydralazine is a direct vasodilatory that can be used for hypertension and heart failure. Benztropine is an older anticholinergic medication originally indicated for Parkinson's disease but most commonly used to manage EPS symptoms from dopamine-blocking agents such as antipsychotics. Tussionex is a combination medication of chlorpheniramine and hydrocodone. It is used to help alleviate cough. Paroxetine is an SSRI used for the treatment of depression, anxiety, and other psychiatric disorders.
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    17 mins
  • Top 200 Drugs Pharmacology Podcast – Drugs 26-30
    Jul 11 2024
    On this episode of the Top 200 Drugs pharmacology podcast, I cover fluticasone nasal spray, allopurinol, alendronate, famotidine, and cefdinir. Fluticasone is a corticosteroid that can be used nasally for the treatment of allergic rhinitis. Allopurinol is a xanthine oxidase inhibitor used to reduce uric acid and prevent gout flares. Alendronate is a bisphosphonate that inhibits the action of osteoclasts. This action helps treat osteoporosis. Famotidine is a histamine-2 receptor antagonist that helps reduce gastric acid secretion and alleviate heartburn symptoms. Cefdinir is a third-generation cephalosporin that is often used as an alternative for those who cannot take penicillin antibiotics. There is a small risk for cross-reactivity that a clinician has to consider.
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    20 mins
  • Top 200 Drugs Podcast – Drugs 21-25
    Jul 4 2024
    Lamotrigine is an antiseizure medication and also may be used for bipolar disorder. A rash is a major side effect to remember with this medication. Valganciclovir is an antiviral medication that can be used to prevent cytomegalovirus (CMV) in patients with a suppressed immune system. Fluconazole is an azole antifungal that can be used to treat candidiasis, blastomycosis, and tinea infections. Drug interactions, QTc prolongation, and hepatotoxicity are potential risks. Atenolol is a beta-blocker used to treat atrial fibrillation and hypertension. It is relatively selective for beta-1 receptors meaning that it doesn't affect the lungs as much as non-selective agents. Montelukast is a medication that blocks the actions of leukotrienes. This can be beneficial for the management of allergies and asthma.
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    14 mins
  • Top 200 Drugs Pharmacology Podcast – Drugs 16-20
    Jun 27 2024
    In this episode of the Real Life Pharmacology podcast, I cover drugs 16-20 of the top 200 drugs. This podcast includes information about clozapine, furosemide, heparin, tetracycline, and vardenafil. Clozapine has five boxed warnings and these are all items that you may see on your pharmacology and board exams! I've also blogged about these in the past at meded101. Furosemide is a loop diuretic and a common indicator of the prescribing cascade. I discuss this in this podcast episode. Heparin can cause thrombocytopenia. I discuss what HIT (heparin-induced thrombocytopenia) may look like.
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    17 mins
  • Top 200 Drugs Pharmacology Podcast – Drugs 11-15
    Jun 20 2024
    Metformin is a medication used in the management of diabetes. It can cause significant diarrhea, B12 deficiency, and in rare cases, lactic acidosis. Atorvastatin (Lipitor) is a statin medication used for cholesterol management. It lowers LDL and is associated with myopathy. Omeprazole is a PPI used for GERD and has drug interactions with citalopram and clopidogrel. Ciprofloxacin is a quinolone antibiotic used to treat gram-negative infections and UTIs. It carries numerous risks such as tendon rupture. Ondansetron is an antiemetic medication used in the management of nausea and vomiting. I discuss the prescribing cascade in relation to this medication.
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    13 mins
  • Top 200 Drugs 6-10 Pharmacology Podcast
    Jun 13 2024
    On this episode of the Real Life Pharmacology podcast, I discuss drugs 6-10 of the top 200 drugs. Included in this podcast episode are two antibiotics that are frequently used in pediatrics. Those two antibiotics are azithromycin and amoxicillin. Alprazolam is a benzodiazepine. It is a controlled substance that is used for the acute relief of anxiety. It is not well tolerated in the elderly. Hydrochlorothiaizde is a thiazide diuretic used primarily for hypertension. It can exacerbate gout and cause frequent urination. Amlodipine is a dihydropyridine calcium channel blocker. The most important adverse effect to remember with this medication is edema.
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    12 mins
  • Top 200 Drugs Podcast – Drugs 1-5
    Jun 6 2024
    On this episode of the Real Life Pharmacology Podcast, I start my journey on summarizing the most highly testable pearls with the top 200 medications. I'm going through the top 200 medications, 5 drugs at a time, and sharing my experience and clinically relevant information about these medications. Escitalopram is an SSRI that can cause serotonin syndrome, sexual dysfunction, and SIADH. Simvastatin is a cholesterol medication that can cause myopathy and rhabdomyolysis. Levothyroxine is a thyroid hormone replacement medication that has numerous binding drug interactions. Vicodin is a brand name combination of hydrocodone and acetaminophen. It is an opioid combined with and OTC analgesic. Lisinopril is an ACE inhibitor used for hypertension that can cause a chronic dry cough and hyperkalemia.
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    16 mins
  • Timolol Pharmacology Podcast
    May 30 2024
    On this episode, I discuss timolol pharmacology, adverse effects, drug interactions, and much more. Timolol is a non-selective beta-blocker so it blocks both beta-1 and beta-2 receptors. Since timolol blocks beta-2 receptors, it can blunt the effect of respiratory medications that have beta-agonist action. Beta-blockers are notorious for causing bradycardia and pulse is an important monitoring parameter for timolol.
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    14 mins