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In this episode of The Metabolic Link, host Victoria Field interviews Dr. Deanna Kelly, a distinguished professor of psychiatry at the University of Maryland School of Medicine. Dr. Kelly is pioneering nutritional interventions to treat serious mental illness and led a groundbreaking trial on the ketogenic diet for schizophrenia, the only inpatient study of its kind in the U.S. Unfortunately, this privately funded trial was recently shut down by the Maryland Department of Health. This interview was recorded before this development.

Despite this setback, Dr. Kelly's insights into metabolic therapies offer new pathways for treating serious mental illness. They discuss the impact of diet on mental health, metabolic dysfunction in mental illness, and personalized medicine. Plus, learn how you can support ongoing research by signing a petition organized by Dr. Chris Palmer to reinstate Dr. Kelly's ketogenic diet trial.

Sign the Petition here

About Dr. Kelly: Deanna L. Kelly, Pharm.D., BCPP, is a Professor of Psychiatry at the University of Maryland School of Medicine and an Affiliate Professor in the School of Pharmacy. She directs the Treatment Research Program at the Maryland Psychiatric Research Center and has been Acting Director since January 2022. An expert in schizophrenia and psychopharmacology, she has published over 235 peer-reviewed articles, coauthored 19 books and chapters, and received the Maltz Prize for her work on gluten and mental health.

Special thanks to the sponsors of this episode: Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink

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In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs: https://membership.metabolicinitiative.com

In this episode of the Metabolic Link Podcast, host Dr. Dom D'Agostino sits down with Dr. Robert Lustig to discuss groundbreaking research unifying different models of obesity. They dive deep into the flaws of the traditional energy balance and carbohydrate-insulin models and introduce a compelling integrative theory encompassing the impact of obesogens, redox biology, and reactive oxygen species (ROS) on metabolic health. The conversation navigates through a review article by Dr. Lustig and others on obesogens from the International Journal of Obesity, dissecting specific obesogens like bisphenol A, phthalates, and glyphosate, and examining how different foods and lifestyle choices can mitigate their effects. This episode is a must-listen for anyone interested in nutritional science, metabolic health, and the future of obesity research.

About Dr. Lustig
Robert H. Lustig, M.D., M.S.L. is Emeritus Professor of Pediatrics in the Division of Endocrinology, and Member of the Institute for Health Policy Studies at UCSF. Dr. Lustig is a neuroendocrinologist, with expertise in metabolism, obesity, and nutrition.

To learn more about Dr. Lustig, please visit: https://robertlustig.com

Special thanks to our sponsors:
Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink

LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at https://drinklmnt.com/metaboliclink

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Referenced Papers:

1. Obesogens: a unifying theory for the global rise in obesity
2. Do We Need a New Unifying Theory for Obesity?

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs: https://membership.metabolicinitiative.com

In this interview, host Victoria Field sits down with Dr. Casey Means, a Stanford-trained physician, entrepreneur, and New York Times bestselling author of the new book Good Energy. Dr. Means shares her inspiring journey from being a head and neck surgeon to leaving traditional medicine and becoming a leading voice in the metabolic health field. They take a deep dive into the environmental factors that impact our metabolism, the importance of taking care of your mitochondria, and practical steps to improve your overall metabolic health and well-being. Dr. Means also shares her own health struggles along the way and even sheds light on the emotional aspects of metabolic health, including the importance of navigating through trauma and making peace with death. Tune in for a conversation that is both informative and deeply personal.

Casey Means, MD is a Stanford-trained physician and co-founder of Levels, a health technology company with the mission of reversing the world’s metabolic health crisis and author of the #1 New York Times bestselling book Good Energy, released May 2024. She received her BA with honors and MD from Stanford, was President of her Stanford class, and has served on Stanford faculty. She trained in Head & Neck Surgery before leaving traditional medicine to devote her life to tackling the root cause of why Americans are sick. She has been featured in The New York Times, The New Yorker, The Wall Street Journal, Forbes, Women’s Health, and more.

To learn more about Dr. Means, to join her newsletter, and get her book, please visit: https://www.caseymeans.com/

Special thanks to our sponsors:
Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink

LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at https://drinklmnt.com/metaboliclink

AirDoctor is an air purifier that filters out 99.99% of dangerous contaminants so your lungs don’t have to. Visit airdoctorpro.com and used promo code METABOLIC LINK to get UP TO $300 of

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs! Registered dietitian, Lily Nichols, RDN, CDE, is back on The Metabolic Link, this time in an intimate interview that dives into the critical links between metabolic health, perinatal nutrition, and long-term wellbeing. This episode dives deep into how nutrition during the childbearing years can affect not only mothers but their children throughout their lives.

Lily, who is also a New York Times bestselling author of key books on prenatal nutrition, unpacks the significance of blood sugar balance, the role of various micronutrients, and the timing and composition of meals in optimizing fertility and pregnancy health. She shares her expertise on managing gestational diabetes through dietary adjustments and explains how both maternal and paternal health can influence pregnancy outcomes.

Additionally, the conversation includes discussions around fertility treatments and assisted reproductive technologies.

About Lily Nichols, RDN, CDE:
Lily Nichols is a Registered Dietitian/Nutritionist, Certified Diabetes Educator, researcher, and author with a passion for evidence-based nutrition. She is the founder of the Institute for Prenatal Nutrition®, co-founder of the Women’s Health Nutrition Academy, and the author of three books: Real Food for Fertility, Real Food for Pregnancy, and Real Food for Gestational Diabetes.

We're hosting a Live Q&A with Lily Nichols as a follow up to this episode on June 12th at 8am PT/11am ET! Bring your questions and join our medical education platform with a FREE 7-day free trial. Click here to register.

Special thanks to our sponsors:
Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink

LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at https://drinklmnt.com/metaboliclink

Timeline, a Swiss based life science company, is a global leader in Urolithin A research. Timeline is offering 10% off your first order of Mitopure. Go to timeline.com/METABOLICLINK & use code METABOLICLINK

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs!

Join us in this enlightening episode as we dive deep into the emerging research behind Urolithin A and its impact on mitochondrial health with Dr. Anurag Singh, a leading expert in the field and the Chief Medical Officer of Timeline.

The discussion spans various facets of Urolithin A, from its origin in pomegranates and other foods to its potential in improving mitochondrial health, muscle strength, and reducing inflammation. Dr. Singh shares insights from his decade-long research on this remarkable compound, discussing everything from the science of mitophagy to its implications for overall health. You’ll also hear about the synergistic effects of combining Urolithin A with other mitochondrial-targeting compounds and therapies like ketogenic diets and exogenous ketones.

The episode also reveals fascinating findings on how Urolithin A interacts with our cellular machinery to combat age-related decline and offers a peek into future applications, including a unique perspective on transdermal delivery systems. Dr. Singh’s expert knowledge sheds light on the exciting future directions of Urolithin A research and its vast potential applications.

About Dr. Anurag Singh:
Dr. Anurag Singh is currently the Chief Medical Officer at Timeline, a company that develops next-generation advanced nutritional products targeting improvements in mitochondrial and muscle health. With an M.D. in internal medicine and a Ph.D. in immunology, his experience includes work for top consumer health and startup/biotech companies. He’s authored more than 40 articles in top science journals and has designed and led more than 50 randomized clinical trials in nutrition.

Learn more about Timeline and Mitopure.

Special thanks to our sponsors of this episode:
Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink

LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at https://drinkLMNT.com/MetabolicLink

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative for exclusive episodes and earn CMEs!

Dive into the core of nutrition science with Dr. Dominic D'Agostino and Dr. Nina Teicholz, and uncover the remarkable benefits of saturated fats, unravel the complexities of LDL cholesterol, and dig into the heated debate surrounding food addiction and ethical meat consumption.

Dr. Teicholz sheds light on the misunderstood facets of dietary fats, debunking prevalent myths about cholesterol, highlighting potential detrimental effects of seed oils, and offering profound insights into how adherence to outdated dietary guidelines impacts both our health and the environment.

Bring your follow up questions on May 16th at 1pm PT/4pm ET to our Live Q&A with Dr. Teicholz on our medical education platform, The Metabolic Initiative. Your first 7 days on the platform are free! Visit this link to register.

To access Dr. Sarah Hallberg's legacy course, please click here. More info on Dr. Teicholz and her latest articles, click here.

Thank you to our sponsors of this episode:
Genova Connect, powered by Genova Diagnostics offers advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Receive 15% off any of their tests with code metaboliclink: https://gdx.net/themetaboliclink

LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at: https://drinkLMNT.com/MetabolicLink

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative for exclusive episodes and to earn CMEs

In this episode, recorded at Metabolic Health Summit 2024, Dr. Richard Johnson dives into the groundbreaking research that has uncovered the central role of fructose in driving the epidemics of obesity, diabetes, and a wide range of other metabolic diseases.

Dr. Johnson presents compelling evidence that fructose, a seemingly innocuous sugar, is in fact a key trigger for activating a powerful biological survival switch. This switch, evolved in nature to help animals prepare for times of scarcity, is now being inadvertently activated in humans by our modern high-carbohydrate, high-sugar diets.

Through detailed scientific explanation and insightful case studies, Dr. Johnson illuminates how fructose's unique metabolic effects - including its ability to lower ATP levels, induce leptin resistance, and promote fat storage - are the driving forces behind the rise of metabolic syndrome and its associated conditions.

Equally important, Dr. Johnson offers practical dietary recommendations and strategies to help individuals navigate this complex landscape, emphasizing the importance of reducing sugar, refined carbs, and processed foods, while embracing a low-carb, nutrient-dense approach.

This eye-opening episode is a must-listen for anyone seeking to understand the root causes of the metabolic health crisis and learn evidence-based solutions to reclaim their wellbeing.

Special thanks to our sponsors:

Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Receive 15% off any of their tests with code metaboliclink: http://gdx.net/themetaboliclink

LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at: drinkLMNT.com/MetabolicLink

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode of The Metabolic Link, Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff dive into a fascinating new paper that compares the metabolic and immune impacts of ketogenic and vegan diets in humans.

The study, titled “Differential Peripheral Immune Signatures Elicited by Vegan Versus Ketogenic Diets in Humans” takes a deep dive into the multi-omic effects of these two very different dietary approaches. The researchers found that just two weeks on a ketogenic diet significantly enhanced markers of adaptive immunity, while the vegan diet was associated with increased innate immune function.

The hosts unpack these findings, discussing the potential mechanisms behind the divergent immune signatures, the limitations of the short-term study design, and the need for further research.

They also highlight the importance of carefully standardizing the macronutrient and micronutrient compositions of the dietary interventions to isolate the key drivers of the observed changes.

Overall, this episode provides a thought-provoking look at the profound impacts that diet can have on the functioning of our immune system, setting the stage for future studies exploring the therapeutic potential of nutritional approaches.

This episode is sponsored by Genova Diagnostics. Genova has been researching and refining precision health testing for decades. It's that experience that has allowed them to create comprehensive assessments that shed light on your individual health status and make recommendations for changes that will bring your wellness into focus.

Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Through Genova Connect, anyone can gain insights into their health and find ways to improve their well-being. Learn more at https://gdx.net/themetaboliclink

As mentioned in the introduction, you can watch the free virtual masterclass co-hosted Genova Diagnostics and Metabolic Health Summit showcasing some of the world-leading experts in metabolic health here.

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.