Showing titles in History & Commentary

In 1932, the US Public Health Service recruited 623 African American men from Macon County, Alabama, for a study of "the effects of untreated syphilis in the Negro male". For the next 40 years - even after the development of penicillin, the cure for syphilis - these men were denied medical care for this potentially fatal disease.

The story of nursing is complicated. It is woven into war, plague, religion, the economy, and our individual lives in myriad ways. In Taking Care, journalist Sarah DiGregorio chronicles the lives of nurses past and tells the stories of those today—caregivers at the vital intersection of health care and community who are actively changing the world, often invisibly.

Over the past 50 years, rates of autoimmunity and chronic disease have exploded. In this provocative book, Dr. Thomas Cowan argues for a direct causal relationship to a corresponding increase in the number of vaccines American children typically receive. The goal of these vaccines is precisely what we’re now seeing in such abundance among our chronically ill children: the provocation of immune response. Cowan looks at emerging evidence that certain childhood illnesses are actually protective of disease later in life.

Smallpox, the only infectious disease to have been eradicated, was one of the most terrifying of human scourges. It covered the skin with hideous, painful boils, killed a third of its victims, and left the survivors disfigured for life. In this riveting, often terrifying look at the history of smallpox, Jonathan B. Tucker tells the story of this deadly disease, the heroic efforts to eradicate it worldwide, and the looming dangers it still poses today.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

The plague that devastated Asia and Europe in the 14th century has been of never-ending interest to both scholars and the general public. Many books on the plague rely on statistics to tell the story. In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

As a psychiatrist in training fresh from medical school, Carl Erik Fisher found himself face-to-face with an addiction crisis that nearly cost him everything. Desperate to make sense of his condition, he turned to the history of addiction, learning that our society’s current quagmire is only part of a centuries-old struggle to treat addictive behavior.

Six decades ago, visionary doctors achieved the impossible: the humble kidney, acknowledged since ancient times to be as essential to life as the heart, became the first human organ to be successfully replaced with a machine. Yet huge dialysis corporations, ambitious doctor-entrepreneurs, and Beltway lobbyists soon turned this medical miracle into an early experiment in for-profit medicine—and one of the nation's worst healthcare catastrophes.

Early studies of the human brain used a simple method: Wait for misfortune to strike - strokes, seizures, infectious diseases, horrendous accidents - and see how victims coped. In many cases their survival was miraculous, if puzzling. Observers were amazed by the transformations that took place when different parts of the brain were destroyed, altering victims' personalities. With the lucid, masterful explanations and razor-sharp wit his fans have come to expect, Kean explores the brain's secret passageways.

Sometimes in medicine the only way to know what is truly going on in a patient is to operate, to look inside with one's own eyes. This book is exploratory surgery on medicine itself, laying bare a science not in its idealized form but as it actually is - complicated, perplexing, and profoundly human.

In virtually every way that can be measured, Gen Z's mental health is worse than that of previous generations. Youth suicide rates are climbing, antidepressant prescriptions for children are common, and the proliferation of mental health diagnoses has not stopped the trend. What has gone wrong with our youth? In Bad Therapy, bestselling investigative journalist Abigail Shrier argues that the problem isn't the kids - it's the mental health experts.

Caroline Crampton’s life was upended at the age of seventeen, when she was diagnosed with Hodgkin’s lymphoma, a relatively rare blood cancer. After years of invasive treatment, she was finally given the all clear. But being cured of the cancer didn’t mean she felt well. Instead, the fear lingered, and she found herself always on the alert, braced for signs that the illness had reemerged.

Jim Geraghty has been a passionate participant in the orphan drug revolution since its inception―a leader in the field as a strategy consultant, biotechnology executive, and venture entrepreneur. His book is in part a history, with eyewitness accounts of advances as they occurred and portraits of the pioneering scientists and physicians, tireless activists, and visionary business leaders who made the revolution happen. And it tells deeply personal stories of patients and parents willing to risk untried new therapies.

Intensive care units and mechanical ventilation are the crucial foundation of modern medical care: without them, the appalling death toll of the COVID-19 pandemic would be even higher. In The Autumn Ghost, Dr. Hannah Wunsch traces the origins of these two innovations back to a polio epidemic in the autumn of 1952. Drawing together testimony from doctors, nurses, medical students, and patients, Wunsch relates a gripping tale of an epidemic that changed the world.

Dr. Jonathan Reisman - a physician, adventure traveler, and naturalist - brings listeners on an odyssey, navigating our insides like an explorer discovering a new world. With unique insight, Reisman shows us how understanding mountain watersheds helps to diagnose heart attacks, how the body is made mostly of mucus, not water, and how urine carries within it a tale of humanity’s origins.

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases.

Now published in five languages, Strange Medicine casts a gimlet eye on the practice of medicine through the ages that highlights the most dubious ideas, bizarre treatments, and biggest blunders. From bad science and oafish behavior to stomach-turning procedures that hurt more than helped, Strange Medicine presents strange but true facts and an honor roll of doctors, scientists, and dreamers who inadvertently turned the clock of medicine backward.

The year is 1925. It is sixty degrees below zero. The wind sweeps tons of snow over the deep-frozen Alaskan landscape. The nearest railhead is seven hundred miles away. Airplanes cannot fly. The way to Nome is blocked by a treacherous frozen sound, an icebound port, and mountains to the west. But there is a diphtheria epidemic in Nome. The children need serum from the outside world if they are to survive. Their only hope is a few chosen Eskimo drivers and their teams of dogs.

Over the past 70 years, the Diagnostic and Statistical Manual of Mental Disorders, or DSM, has evolved from a virtually unknown and little-used pamphlet to an imposing and comprehensive compendium of mental disorder. Its nearly 300 conditions have become the touchstones for the diagnoses that patients receive, students are taught, researchers study, insurers reimburse, and drug companies promote.

The modern healthcare system has become proficient at staving off death with aggressive interventions. And yet, eventually everyone dies - and although most Americans say they would prefer to die peacefully at home, more than half of all deaths take place in hospitals or health care facilities. At the End of Life tackles this conundrum head on. Featuring 22 compelling personal-medical narratives, the collection explores death, dying, and palliative care, and highlights current features, flaws, and advances in the healthcare system.