Human Genetic Engineering

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

In our unique genomes, every one of us carries the story of our species - births, deaths, disease, war, famine, migration, and a lot of sex. But those stories have always been locked away - until now. Who are our ancestors? Where did they come from? Geneticists have suddenly become historians, and the hard evidence in our DNA has completely upended what we thought we knew about ourselves. Acclaimed science writer Adam Rutherford explains exactly how genomics is completely rewriting the human story - from 100,000 years ago to the present.

You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.

What is human consciousness, and how is it possible? This question fascinates thinking people from poets and painters to physicists, psychologists, and philosophers. From Bacteria to Bach and Back is Daniel C. Dennett's brilliant answer, extending perspectives from his earlier work in surprising directions, exploring the deep interactions of evolution, brains, and human culture.

Book 5: Free the North!: Peace in the south. People settling in. Intelligent creatures moving to Vii from the RV Traveler. Soon, meat will be in short supply. Hungry people will fight for what they need. Braden knows that livestock abounds in the north. It's time to go get some. But free trade in the north has been declared illegal by a new governor.

In this groundbreaking work, evolutionary biologist Jared Diamond stunningly dismantles racially based theories of human history by revealing the environmental factors actually responsible for history's broadest patterns. It is a story that spans 13,000 years of human history, beginning when Stone Age hunter-gatherers constituted the entire human population. Guns, Germs, and Steel is a world history that really is a history of all the world's peoples, a unified narrative of human life.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

There is no one better qualified than Jared Diamond - renowned expert in the fields of physiology and evolutionary biology and award-winning author - to explain the evolutionary forces that operated on our ancestors to make us sexually different. With wit and a wealth of fascinating examples, he explains how our sexuality has been as crucial as our large brains and upright posture in our rise to human status.

Having done field work in New Guinea for more than 30 years, Jared Diamond presents the geographical and ecological factors that have shaped the modern world. From the viewpoint of an evolutionary biologist, he highlights the broadest movements both literal and conceptual on every continent since the Ice Age, and examines societal advances such as writing, religion, government, and technology.

In A Story of Us, they present this rich narrative and explain how the evolution of our genes relates to the evolution of our cultures. Newson and Richerson take listeners through seven stages of human evolution, beginning seven million years ago with the apes that were the ancestors of humans and today's chimps and bonobos. The story ends in the present day and offers a glimpse into the future.

In this eye-opening work, Graziano accessibly explores how this sense of an inner being led to empathy and formed us into social beings. The theory may point the way to engineers for building consciousness artificially. Graziano discusses what a future with artificial consciousness might be like, including both advantages and risks, and what AI might mean for our evolutionary future.

Humans live in landscapes of make-believe. We spin fantasies. We devour novels, films, and plays. Even sporting events and criminal trials unfold as narratives. Yet the world of story has long remained an undiscovered and unmapped country. It's easy to say that humans are "wired" for story, but why? In this delightful and original book, Jonathan Gottschall offers the first unified theory of storytelling. He argues that stories help us navigate life's complex social problems.

Why can humans alone invent? In The Pattern Seekers, Cambridge University psychologist Simon Baron-Cohen makes a case that autism is as crucial to our creative and cultural history as the mastery of fire. Indeed, Baron-Cohen argues that autistic people have played a key role in human progress for 70,000 years, from the first tools to the digital revolution. How? Because the same genes that cause autism enable the pattern seeking that is essential to our species' inventiveness.

Sex, Time, and Power offers a tantalizing answer to an age-old question: Why did big-brained Homo sapiens suddenly emerge some 150,000 years ago? The key, according to Shlain, is female sexuality. Drawing on an awesome breadth of research, he shows how, long ago, the narrowness of the newly bipedal human female's pelvis and the increasing size of infants' heads precipitated a crisis for the species. Natural selection allowed for reconfiguration of hormonal cycles, entraining women with the periodicity of the moon - and imbuing women with the concept of time.

V. S. Ramachandran is at the forefront of his field - so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience". Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved.

Racist pseudoscience is on the rise - fueling hatred, feeding nationalism, and seeping into our discourse on everything from sports to intelligence. Even the well-intentioned repeat stereotypes based on "science", because cutting-edge genetics are hard to grasp - and all too easy to distort. Paradoxically, misconceptions are multiplying amid today's unprecedented surge of research on human genetics. We've never had a clearer picture of who we are and where we come from, and the science, when accurately understood, is a powerful and definitive ally against racism.

A Pocket History of Human Evolution brings us up-to-date on the exploits of all our ancient relatives. Paleoanthropologist Silvana Condemi and science journalist François Savatier consider what accelerated our evolution: Was it tools, our "large" brains, language, empathy, or something else entirely? And why are we the sole survivors among many early bipedal humans? Their conclusions reveal the various ways ancient humans live on today - from gossip as modern "grooming" to our gendered division of labor - and what the future might hold for our strange and unique species. 

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

In this audiobook, The Human Odyssey, we explore the evolution of those characteristics that make us human. The first section looks at our family tree and why some branches survived and not others. Swings in climate are emerging as a factor in what traits succeeded and failed; meanwhile, DNA analyses show that Homo sapiens interbred with other human species, which played a key role in our survival. 

In The Genealogical Adam and Eve, S. Joshua Swamidass tests a scientific hypothesis: What if the traditional account is somehow true, with the origins of Adam and Eve taking place alongside evolution? Building on well-established but overlooked science, Swamidass explains how it's possible for Adam and Eve to be rightly identified as the ancestors of everyone.