The word ‘methylation’ has become somewhat of a buzz word in functional and personalized medicine. We’ve mentioned it several times throughout many episodes of The Lab Report – hard to avoid since it’s involved in just about every biological process.

In today’s episode, we finally hit the topic of methylation head on and dive into the methylation cycle itself. What is it? Why should you care? Although biochemistry can be intimidating, listen as we simplify and demystify the steps involved. You may find it helpful to refer to a Methylation Pathway Chart while listening to this one!

Today on The Lab Report:

• 2:00 What is methylation and why is it clinically important
• 5:30 Jumping into the biochemistry – metaphors to the rescue!
• 11:35 Homocysteine
• 14:00 The main pathway versus back up pathway
• 19:33 Transsulfuration
• 22:30 Multi-omics and the methylation cycle
• 27:50 Question of the Day
  • “What does it mean if homocysteine is low?”

Additional Resources:

Genova's Methylation Panel

Dr. Michael Chapman's Methylation Webinar

Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Everest Goldstein is a board-certified Psychiatric Nurse Practitioner who is also certified in Functional Medicine and has an extensive background in integrative wellness interventions. She deeply cares about her patients and devotes her time to working closely with each of them to address their individual needs. Knowing the importance of the brain-body connection, Everest addresses the body as a whole to optimize health and wellness.

In today’s episode, we dive into the root causes of mood disorders and psychiatric illness with Everest Goldstein. Everest discusses how nutrition, diet, and lifestyle can contribute to mental health and wellness. If you are struggling mentally, emotionally, or physically, Everest is here to help you regain your life.

Today on The Lab Report:

• 4:30 Meet Everest Goldstein and hear about her passion for psychiatry
• 7:45 Everest’s unique approach to mental health
• 9:55 The debate of mental health root causes
• 12:15 Gut microbiome and the brain connection
• 16:50 Nutrition changes for better outcomes
• 20:00 Using the ketogenic diet in mental illness
• 23:50 Protein, amino acids, and neurotransmitters
• 26:00 The role for psychiatric medications
• 28:30 Coaching lifestyle changes and motivation
• 31:50 Therapy and counseling
• 35:12 The Fireball

Additional Resources:

Everest Functional Psychiatry and Wellness

Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Berberine is an alkaloid compound that can be extracted from several plants. It is a widely used supplement in personalized medicine and is also beginning to get some traction within the conventional medicine space. Berberine is mainly used in the GI tract for its antimicrobial effects, but as it relates to gut health, that’s just the tip of the iceberg. What is even more fascinating is berberine’s vast systemic metabolic influences.

In today’s episode, we dive into the wide array of berberine’s important effects. Not only on the gut, but also on detoxification systems, skin, eyes, lipid and blood glucose control, hypertension, and cardiovascular health.

Today on The Lab Report:

• 4:00 Berberine – not an herb – where does it come from?
• 6:55 Overall gut modulator, skin health, and detox
• 13:05 Metabolic dysfunction – blood glucose, protein, lipids
• 14:50 Cardiovascular effects and heart health
• 16:00 Contraindications and safety considerations
• 18:00 What’s in a name?

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.