In this episode, we delve into the pivotal role of the BHMT gene within the body's methylation process.

We discuss how the BHMT enzyme is essential for catalyzing a vital reaction that transforms homocysteine into methionine.

Additionally, we cover the importance of betaine in enhancing the methylation cycle. Betaine acts as a methyl donor, particularly in the reaction facilitated by the BHMT enzyme, making it crucial for reducing homocysteine levels and supporting cardiovascular and neurological health.

We also explore the complexity of methylation pathways and emphasize the need for a comprehensive evaluation of multiple genes to truly understand and optimize methylation.

Be sure to follow our podcast for more expert insights into how betaine, methylation, and genetics can be leveraged to optimize both body and brain health.

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

In this episode, Joe tackles a controversial new study that suggests even 25 milligrams of niacin could potentially increase the risk of heart disease.

Delving deep into the world of niacin supplementation, Joe discusses how, despite these concerns, niacin offers numerous health benefits, including enhanced cognitive function, better mood, and increased energy levels.

Joe draws on personal experiences to compare the negatives against the significant positives of niacin, as he explores niacin's biochemical effects, particularly its interaction with proteins such as 2PY, 4PY, and VCAM1, all linked to cardiovascular health.

Throughout the episode, Joe examines the importance of dosage, sharing insights into the varying effects of low versus high doses of niacin.

Join Joe as he navigates the complexities of niacin use, advocating for a well-informed, nuanced approach to its benefits and risks.

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

In this episode, we explore the complex interplay between the CNR1 gene, cannabinoid receptors, and cannabis.

Discover the role of the endocannabinoid system in maintaining bodily balance, particularly in brain function, mood regulation, and inflammation response.

We delve deep into how genetic variations in the CNR1 gene can influence the CB1 receptors, and the implications of CB1 receptor function in managing stress, anxiety, and cognitive processes such as memory and decision-making.

Whether you're curious about the science behind getting high or looking for ways to optimize your cannabinoid system through diet and supplements like CBD oil, this episode has something for everyone.

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/