Cracked the Genetic Code! Methylation and the Future of Precision Medicine

This is the second half of the two part series to Dr. Stanford’s presentation called, “Optimizing Healthspan and Longevity by Implementing Personalized Precision Medicine.” For this episode, we dive into the science of methylation patterns and how we can use it to detect various cancers and their tissue origins enabling early intervention for better treatment outcomes and ultimately paving the way for tailored therapies. Similar to the last episode, there are supporting graphics and diagrams so we highly recommend watching this episode on our YouTube channel as this discussion does get pretty technical in various parts of the conversation.

Timestamps:

[00:04:22] Detecting cancer through DNA methylation patterns.

[00:08:56] DNA sequencing reveals gene expression patterns.

[00:12:15] Cancer turns off genes, DNA sequencing detects.

[00:16:01] Detect tumor DNA in bloodstream. Identify cancer signal.

[00:19:20] Methylation patterns in DNA detect cancer.

[00:22:55] Screening for cancer over fifty. Insurance doesn't cover yet.

[00:26:09] Precision medicine case study on heart health.

[00:29:25] Imaging center found life-saving genetic risk.

[00:32:24] Personalized medicine increases health span, reduces costs.

Dr. William Stanford MD PHD FACP

Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. Since 2018, he has provided genomic and precision medicine consultations through the Beverly Hills Institute for Precision Medicine, enhancing his role as a leading expert in the field.

Sponsored by: Biography Health

Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.