In this episode, Dr. Stavros Zanos, a renowned researcher at the Feinstein Institutes for Medical Research, discusses the potential of focused ultrasound neuromodulation in treating a wide range of cardiovascular and inflammatory diseases. Dr. Zanos explains how ultrasound activates neurons through mechanosensitive channels and shares the promising results of recent studies using neuromodulation to treat pulmonary arterial hypertension, reduce inflammatory markers, and potentially manage type 2 diabetes. Learn about the importance of precision in ultrasound neuromodulation to ensure accurate targeting of specific areas in the abdomen. This episode offers a fascinating glimpse into the future of medicine, where focused ultrasound neuromodulation could significantly impact the treatment of millions of patients worldwide.

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Dr. Daniel Jeanmonod, a renowned functional neurosurgeon, joins us upon his retirement to reflect on his pioneering career. Since 1989, Dr. Jeanmonod has been at the forefront of focused ultrasound research and treatment for neuropathic pain, Parkinson's disease, and essential tremor. He recounts his groundbreaking achievement in using noninvasive focused ultrasound to treat patients at the University Children's Hospital of Zurich. He also discusses the establishment of the SoniModul Center of Ultrasound Functional Neurosurgery in Zurich and the center's impressive track record over its 14-year history. Dr. Jeanmonod shares fascinating patient stories that highlight the profound impact of focused ultrasound treatments on individuals suffering from chronic, therapy-resistant neuropathic pain. He also emphasizes the importance of considering the psycho-emotional aspects of pain management and the role of psychotherapy in optimizing treatment outcomes. Throughout the conversation, Dr. Jeanmonod offers valuable advice for young neurosurgeons interested in using focused ultrasound in functional neurosurgery. He stresses the significance of understanding the underlying mechanisms of brain disorders.

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This episode features an insightful discussion on the potential of focused ultrasound in revolutionizing women's health care. The conversation, moderated by Dr. Jessica Foley, Chief Scientific Officer at the Focused Ultrasound Foundation, includes expert panelists Dr. Suzanne LeBlang, neuroradiologist and Director of Clinical Relationships at the Focused Ultrasound Foundation, Dr. Lynn Dengel, surgical oncologist at UVA Health, and Dr. Elisa Konofagou, professor of biomedical engineering and radiology at Columbia University. The discussion highlights the versatility of focused ultrasound in treating a wide range of conditions that disproportionately affect women, such as uterine fibroids, breast tumors, Alzheimer's disease, chronic pain, depression, and anxiety. The panelists share their experiences and research in using focused ultrasound for various applications, including ablation, immunotherapy, neuromodulation, and opening the blood-brain barrier for drug delivery. The experts also address the challenges faced in advancing focused ultrasound for women's health, including the need for more clinical trials with female participants, raising awareness among clinicians and patients, and securing insurance coverage. They emphasize the importance of collaboration among researchers, clinicians, and regulatory bodies to accelerate the translation of focused ultrasound technologies from bench to bedside. This engaging discussion offers valuable insights into the current state and future potential of focused ultrasound in improving the lives of women affected by a variety of health conditions. The episode also highlights the Focused Ultrasound Foundation's efforts in supporting research, fostering collaboration, and advocating for focused ultrasound as a transformative tool in women's health care.

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