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Grab your coffee and join Kevin and Brian for a lively AMA that tackles everything from turning 50 to the mysteries of VO2 Max. They’ll chat about the power of small decisions, the importance of lean muscle and sleep, and why living in communities matters more than ever. Plus, they’ll decode Norwegian 4x4s (not what you think) and spill their MVP supplement list. Expect laughs, insights, and a few surprises in this fun, irreverent episode of The Daily Apple!

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The Daily Apple: Exploring Rapamycin and the Science of Aging with Dr. Matt Kaeberlein

In this enlightening episode of *The Daily Apple*, Kevin sits down with renowned biogerontologist Dr. Matt Kaeberlein to dive deep into the science behind Rapamycin, a powerful small molecule drug known for extending lifespan and enhancing health span. Discover how this intriguing compound mimics caloric restriction, slows the division of competing cells, and what it means for the future of aging.

Dr. Kaeberlein also breaks down the "pharmacokinetics" of Rapamycin, explores its potential benefits based on groundbreaking research in non-human primates, and discusses the 12 hallmarks of aging. Whether you're curious about the latest in longevity research or looking to understand how science is pushing the boundaries of human health, this episode is packed with insights you won’t want to miss.

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In this episode, Cliff Edberg, a licensed dietitian and personal trainer, shares his inspiring journey from childhood obesity to becoming a bodybuilding champion and fitness expert. Cliff discusses his holistic approach to wellness, drawing from his experience as 'trainer to the trainers" at Life Time and his new position with Lifetime's MIORA Performance and Longevity program.

Learn about precision health, metabolic optimization, and proactive wellness strategies to help you achieve lasting fitness and health. Tune in for actionable advice, personal stories, and insights that will motivate you to unlock your true potential.

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Thrilled to sit down for a fascinating conversation with longevity expert & avid cyclist Dr. Benjamin Miller from Oklahoma Medical Research Foundation & the President of the American Aging Association. I’ve been looking forward to our conversation for a long time. He is truly an authority in this space, and I learned a lot during our discussion.

We get to dive deep into the latest research concerning cellular energetics (mitochondrial dysfunction), and lean muscle maintenance (proteostasis), how they relate to aging, the importance of ‘energy on demand’ and steps we can take to slow this progression of decline, having a more robust healthy life.

Dr. Miller brings a fresh perspective to the conversation, challenging us to shift our mindset from ‘purposeful exercise’ to simply, ‘physical activity’ - how that along has tremendous benefits. The idea of exercise can be a bit daunting to many. Instead, simply focusing on making that first step- because going from doing nothing to doing something reaps huge dividends.

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How in the world do we explain this episode? Today we have a conversation with my friend Brian Piccolo, who sounds like Bruce Springsteen and has spent his life "living like a boss" (forgive the Dad joke, but it had to be done).

From high school wrestling beginner to college wrestling punch bag to finally All American overcomer and Olympic hopeful. And when that was done, on to Judo on a whim...and one questionable call away from the Olympics.

The best way to describe this conversation is just to drop in some of the juicy one liners that peppered this pod and kept us coming back for more...and more...and more. And now, in no particular order, some nuggets for you...

Judo, it’s like wrestling in pajamas.

You know, all the illegal stuff from wrestling? You can do it in judo!

Are you on the path? Look how far you’ve come.

When you get through this, you’ll be better on the other side.

And last, but not least...

Would the “you” of today SMASH the “you” of 6 months ago?

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On today's episode I'm talking with Dr. Mary Pardee, a renowned expert in the field of gut health and optimization. She is based in Los Angeles, California, and has established herself as a leading voice in the understanding and treatment of gastrointestinal issues and their connection to overall health.

In this episode, we delve into 2 big issues- gut health and sleep optimization. We discuss her insights and approach to gut health, the gut microbiome, the gut-brain connection, along with her own personal journey with this issue. We then shift gears to speak about sleep optimization - which stems from her personal story of a concussion sustained during a boating accident, leading to sleep issues, and how that was eventually treated with cognitive behavioral therapy for insomnia (CBTI).

And check out Dr Mary Pardee on Instagram or at modrnmed.com or her brand new podcast!

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Emma and I had a quick "download style" discussion about the importance and benefits of Vitamin D. Below are a few of the points we hit on in our conversation.

Did you know...

• Why you need more vitamin D?
• How much do you need?
• How much is “too much”?

And did you know about these benefits and effects of Vitamin D:

• Immune system regulation
• Cell differentiation and growth
• Muscle function and strength
• Cardiovascular health
• Blood pressure management
• Neurologic health
• Anti-inflammatory
• Cytokine release

Vitamin D receptors are spread all throughout the body...

The more you learn, the more you realize how essential Vitamin D is.

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Today is all about a great conversation with our friend Seneca Dewbre, who owns @okiepuncture. Acupuncture is one of those "if you know, you know" topics within the medical community that's not often talked about, but often used. We asked some of the most common questions as well as branching into other areas we've discussed in previous episodes (ice baths and saunas) as well as how it fits into a lifestyle focused on wellness and longevity.

If you're interested in some more detailed information, you can read an author manuscript here that discusses some of the benefits of acupuncture.

Have more questions? Let us know by sending a message here on our instagram so we can always give you the information you're looking for!

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