Showing titles in History & Commentary

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Some of the cruelest deeds of Japan's war in Asia did not occur on the battlefield, but in quiet, antiseptic medical wards in obscure parts of China. Far from front lines and prying eyes, Japanese doctors and their assistants subjected human guinea pigs to gruesome medical experiments in the name of science and Japan's wartime chemical and biological warfare research. Author Hal Gold draws upon a wealth of sources to construct a portrait of the Imperial Japanese Army's most notorious medical unit, giving an overview of its history and detailing its most shocking activities.

A wide-ranging and provocative look - teeming with little-known facts and engaging stories - at a subject of the direst interest. Poisons permeate our world. They are in the environment, the workplace, the home. They are in food, our favorite whiskey, medicine, well water. They have been used to cure disease as well as incapacitate and kill. They smooth wrinkles, block pain, stimulate, and enhance athletic ability. In this entertaining and fact-filled audiobook, science writer Peter Macinnis considers poisons in all their aspects. He recounts stories of the celebrated poisoners in history and literature....

This is a book of miracles - medical events witnessed by leading physicians for which there is no reasonable medical explanation, or, if there is, the explanation itself is extraordinary. These dramatic first-person essays detail spectacular serendipities, impossible cures, breathtaking resuscitations, extraordinary awakenings, and recovery from unimaginable disasters. Miracles We Have Seen is a book of inspiration and optimism, and a compelling glimpse into the lives of physicians.

The Tudor dynasty died out because there was no heir of Elizabeth I's body to succeed her. Henry VIII, despite his six marriages, had produced no legitimate son who would live into old age. Three of the reigning Tudors (Edward VI, Mary I, and Elizabeth I) died without heirs apparent, the most tragic case being that of Mary Tudor, who went through two recorded cases of phantom pregnancy. If it were not for physical frailty and the lack of reproductive health among the Tudors, the course of history might have been different.

How the Brain Lost Its Mind tells the rich and compelling story of two confounding ailments, syphilis and hysteria, and the extraordinary efforts to confront their effects on mental life. How does the mind work? Where does madness lie, in the brain or in the mind? How should it be treated?

Drawn from historical records and current news headlines, A Taste for Poison weaves together the tales of spurned lovers, shady scientists, medical professionals, and political assassins to show how the precise systems of the body can be impaired to lethal effect through the use of poison. From the deadly origins of the gin and tonic cocktail to the arsenic-laced wallpaper in Napoleon’s bedroom, A Taste for Poison leads listeners on a fascinating tour of the intricate, complex systems that keep us alive - or don’t.

The story of poison is the story of power. For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family's spoons, tried on their underpants, and tested their chamber pots. Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions.

A fascinating account of the world’s most famous disease - polio - told as you have never heard it before. Epidemics of paralysis began to rage in the early 1900s, seemingly out of nowhere. Doctors, parents, and health officials were at a loss to explain why this formerly unheard-of disease began paralyzing so many children. Why did this disease start to become such a horrible problem during the late 1800s? Why did it affect children more often than adults? Why was it originally called teething paralysis by mothers and their doctors?

A good book may have the power to change the way we see the world, but a great book actually becomes part of our daily consciousness, pervading our thinking to the point that we take it for granted, and we forget how provocative and challenging its ideas once were - and still are. The Structure of Scientific Revolutions is that kind of book.

The 1964 murder of a nationally known cancer researcher sets the stage for this gripping exposé of medical professionals enmeshed in covert government operations over the course of three decades. Following a trail of police records, FBI files, cancer statistics, and medical journals, this revealing book presents evidence of a web of medical secret-keeping that began with the handling of evidence in the JFK assassination and continued apace....

In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth merchant, Antonie van Leeuwenhoek, look down their handmade microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christens them 'cells'.

This is the enormously entertaining story of how a fraudulent surgeon made a fortune by inserting goats' testes into impotent American men. "Doctor" John Brinkley became a world renowned authority on sexual rejuvenation in the 1920s, with famous politicians and even royalty asking for his services.

When Rachel Somerstein had an unplanned C-section with her first child, the experience was anything but the “routine” operation her doctor described. A series of errors by her clinicians led to a real-life nightmare: surgery without anesthesia. The ensuing mental and physical complications left her traumatized and desperate for answers about how things could have gone so wrong. In the United States, one in three babies is born via C-section, a rate that has grown exponentially over the past fifty years.

Dr. Jonathan Reisman - a physician, adventure traveler, and naturalist - brings listeners on an odyssey, navigating our insides like an explorer discovering a new world. With unique insight, Reisman shows us how understanding mountain watersheds helps to diagnose heart attacks, how the body is made mostly of mucus, not water, and how urine carries within it a tale of humanity’s origins.

In the spring of 1812, Napoleon Bonaparte was at the height of his powers. Forty-five million called him emperor, and he commanded a nation that was the richest, most cultured, and advanced on earth. No army could stand against his impeccably trained, brilliantly led forces, and his continued sweep across Europe seemed inevitable.

Part memoir, part illuminating treatise on why science is looking to the past for the future of medicine, Unlocking the Ancient Secrets to Healing chronicles the personal tribulations and professional discoveries behind the remarkable realization of Gail Lynn’s dream.

Still Not Safe is the story of the rise of the patient - safety movement - and how an "epidemic" of medical errors was derived from a reality that didn't support such a characterization. Physician Robert Wears and organizational theorist Kathleen Sutcliffe trace the origins of patient safety to the emergence of market trends that challenged the place of doctors in the larger medical ecosystem.

In 1959, a Cincinnati pharmaceutical firm, the William S. Merrell Company, quietly began distributing samples of an exciting new wonder drug already popular around the world. Touted as a sedative without risks, thalidomide was handed out freely, under the guise of clinical trials, by doctors who believed approval by the Food and Drug Administration was imminent. But in 1960, when the application for thalidomide landed on the desk of FDA medical reviewer Frances Kelsey, she quickly grew suspicious.