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How We Age
- The Science of Longevity
- Narrated by: Rosemary Benson
- Length: 19 hrs and 38 mins
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Publisher's summary
All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging. Understanding the fundamental biological rules that govern aging in model systems provides clues about how we might slow human aging, which could lead in turn to new therapeutics and treatments for age-related disease.
Among other vivid examples, Murphy describes research that shows how changing a single gene in the nematode worm C. elegans doubles its lifespan, extending not only the end of life but also the youthful, healthy part of life. Drawing on work in her own lab as well as other recent research, Murphy chronicles the history and current state of the field, explaining longevity's links to reproduction and mating, sensory and cognitive function, inheritances from our ancestors, and the gut microbiome. Written with clarity and wit, How We Age provides a guide to the science: what we know about aging, how we know what we know, and what we can do with this new knowledge.
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Story
Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.
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Decent Overview. Could lose sarcasm.
- By A. Toomey on 06-18-20
By: Nessa Carey
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Ending Aging
- The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime
- By: Aubrey de Grey, Michael Rae
- Narrated by: Stephanie Murphy
- Length: 16 hrs and 4 mins
- Unabridged
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A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging.
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Overly wordy
- By Richard on 03-10-17
By: Aubrey de Grey, and others
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Why We Remember
- Unlocking Memory's Power to Hold on to What Matters
- By: Charan Ranganath
- Narrated by: Mark Deakins, Charan Ranganath
- Length: 7 hrs and 18 mins
- Unabridged
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A new understanding of memory is emerging from the latest scientific research. In Why We Remember, pioneering neuroscientist and psychologist Charan Ranganath radically reframes the way we think about the everyday act of remembering. Combining accessible language with cutting-edge research, he reveals the surprising ways our brains record the past and how we use that information to understand who we are in the present, and to imagine and plan for the future.
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Extremely informative
- By Ash Parker on 07-10-24
By: Charan Ranganath
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1917
- Lenin, Wilson, and the Birth of the New World Disorder
- By: Arthur Herman
- Narrated by: Stefan Rudnicki
- Length: 16 hrs and 36 mins
- Unabridged
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In this incisive, fast-paced history, New York Times best-selling author Arthur Herman brilliantly reveals how Lenin and Wilson rewrote the rules of modern geopolitics. Through the end of World War I, countries marched into war only to increase or protect their national interests. After World War I, countries began going to war over ideas. Together, Lenin and Wilson unleashed the disruptive ideologies that would sweep the world, from nationalism and globalism to Communism and terrorism, and that continue to shape our world today.
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Another book you wish was part of every university world history curriculum
- By BeZot on 11-26-18
By: Arthur Herman
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Prophet Song
- By: Paul Lynch
- Narrated by: Gerry O'Brien
- Length: 8 hrs and 32 mins
- Unabridged
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On a dark, wet evening in Dublin, scientist and mother of four Eilish Stack answers her front door to find the GNSB on her step. Two officers from Ireland’s newly formed secret police are here to interrogate her husband, a trade unionist. Ireland is falling apart. The country is in the grip of a government turning towards tyranny and when her husband disappears, Eilish finds herself caught within the nightmare logic of a society that is quickly unravelling.
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Painfully powerful Tale.
- By Tom on 01-30-24
By: Paul Lynch
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Quanta and Fields
- The Biggest Ideas in the Universe
- By: Sean Carroll
- Narrated by: Sean Carroll
- Length: 9 hrs and 49 mins
- Unabridged
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Sean Carroll is creating a profoundly new approach to sharing physics with a broad audience, one that goes beyond analogies to show how physicists really think. He cuts to the bare mathematical essence of our most profound theories, explaining every step in a uniquely accessible way. Quantum field theory is how modern physics describes nature at its most profound level. Starting with the basics of quantum mechanics itself, Sean Carroll explains measurement and entanglement before explaining how the world is really made of fields.
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amazingly nice introduction Into the complicated field
- By Amazon Customer on 08-11-24
By: Sean Carroll
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The Guns of August
- By: Barbara W. Tuchman
- Narrated by: Wanda McCaddon
- Length: 19 hrs and 9 mins
- Unabridged
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In this Pulitzer Prize-winning classic, historian Barbara Tuchman brings to life the people and events that led up to World War I. This was the last gasp of the Gilded Age, of Kings and Kaisers and Czars, of pointed or plumed hats, colored uniforms, and all the pomp and romance that went along with war. How quickly it all changed...and how horrible it became.
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Wonderful
- By Mike From Mesa on 10-28-08
What listeners say about How We Age
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Soren
- 03-28-24
No PDF
The fact that this book does not have a pdf was a sure fire way to age me drastically. Unless Chemistry is one of your favorite subjects you will constantly listen to every other word being a group of letters you cant remember what they stand for. This was a good book, but until they include a pdf, do not buy it as an audible book--unless your want to reduce your longevity thru immense frustration.
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- Sotirios
- 05-26-24
Excellent
Science based. Integrates the most recent scientific discoveries in a well organized context of aging and aging-related diseases. Balanced regarding hype and reality. Paves a clear path for the most promising technologies for future ant-aging therapies.
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- Jurisa-San
- 01-24-24
Modern science explanation how to slow aging.
The book explains how scientists have been able to probe the molecular mechanisms of longevity and aging by studying model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods. It also describes how longevity is linked to reproduction and mating, sensory and cognitive function, inheritances from our ancestors, and the gut microbiome. Understanding the fundamental biological rules that govern aging in model systems provides clues about how we might slow human aging.
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- Inga
- 04-24-24
Only for Professionals
As a normal human being you won't understand the single word of she's talking.
I've read or listened to a lot of books about aging.
but this one is absolutely lacking the translation into life. It is all about what she tested in which worm and how the which fly is used to see this or that pathway but it's not usable for the average person.
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