Showing results for "Barry Werth" in All Categories

Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading. Coming at a time of economic recession and declining technological competitiveness in the United States, the event ignited a period of speculative frenzy over biotechnology.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.

Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. From Breakthrough to Blockbuster focuses on both the companies themselves and the broader biotech ecosystem that supports them.

Everyone covers. To cover is to downplay a disfavored trait so as to blend into the mainstream. Because all of us possess stigmatized attributes, we all encounter pressure to cover in our daily lives. Given its pervasiveness, we may experience this pressure to be a simple fact of social life. Against conventional understanding, Kenji Yoshino argues that the demand to cover can pose a hidden threat to our civil rights.

A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made “the impossible possible”—creating, testing, and manufacturing a safe and effective COVID-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer overcame a series of crises that were compounded by social and political unrest.

Originally written in Icelandic in the 13th century AD by an anonymous author, The Story of The Volsungs is a legendary saga based on Norse mythology. The epic describes the legendary history and heroic feats of several generations of mythic Viking families and derives from many sources, including preexisting Edda, or heroic poems, Norse legends, historical events, and orally transmitted folklore. The saga is imbued throughout with themes of power, jealousy, love, vengeance, and fear.

In this “monumental and impressive” biography, Max Boot, the distinguished political columnist, illuminates the untold story of Ronald Reagan, revealing the man behind the mythology. Drawing on interviews with over one hundred of the fortieth president’s aides, friends, and family members, as well as thousands of newly available documents, Boot provides “the best biography of Ronald Reagan to date” (Robert Mann).

How Life Imitates Chess is a primer on how to think, make decisions, prepare strategies, and anticipate the future. Kasparov has distilled the lessons he learned over a lifetime as a chess grandmaster to cover the practical side - tactics, strategy, preparation, as well as the subtler, more human arts of using memory, intuition, and imagination.

The Big Miss is Hank Haney's candid and surprisingly insightful account of his tumultuous six-year journey with Tiger Woods, during which the supremely gifted golfer collected six major championships and rewrote golf history. Hank was one of the very few people allowed behind the curtain. He was with Tiger 110 days a year, spoke to him over 200 days a year, and stayed at his home up to 30 days a year, observing him in nearly every circumstance....

In 1952, John T. “Jack” Downey, a 23-year-old CIA officer from Connecticut, was shot down over Manchuria during the Korean War. The pilots died in the crash, but Downey and his partner Richard “Dick” Fecteau were captured by the Chinese. For the next 20 years, they were harshly interrogated, put through show trials, held in solitary confinement, placed in reeducation camps, and toured around China as political pawns.

In America’s collective consciousness, Pat Nixon has long been perceived as enigmatic. She was voted “Most Admired Woman in the World” in 1972 and made Gallup Poll’s top ten list of most admired women fourteen times. She survived the turmoil of the Watergate scandal with her popularity and dignity intact. The real Pat Nixon, however, bore little resemblance to the woman so often described as elusive, mysterious and “plastic” in the press. Pat married Richard Nixon in June of 1940. As the couple rose to prominence, Pat became Second Lady from 1953-1961 and then First Lady from 1969-1974.

In This is Real and You Are Completely Unprepared, author Alan Lew has marked out a journey of seven distinct stages, one that draws on these rituals to awaken our soul and wholly transform us. Weaving together Torah readings, Buddhist parables, Jewish fables, and stories from his own life, Lew lays bare the meanings of this ancient Jewish passage. He reveals the path from terror to acceptance, confusion to clarity, doubt to belief, and from complacency to awe.

In 1998, William Queen was a veteran law-enforcement agent with a lifelong love of motorcycles and a lack of patience with paperwork. When a "confidential informant" made contact with his boss at the Bureau of Alcohol, Tobacco and Firearms, offering to take an agent inside the San Fernando chapter of the Mongols (the scourge of Southern California, and one of the most dangerous gangs in America), Queen jumped at the chance.